Engineering medical-grade, star-lumen kink-resistant Nasal Oxygen Cannulas for adult, pediatric, and neonatal care. Manufactured in Class 10,000 cleanrooms and exported to over 52 countries since 1994.
Multi-channel internal geometry guarantees uninterrupted oxygen flow even if the tubing is severely bent, folded, or compressed.
Formulated with medical-grade, non-leaching plasticizers (DEHP-Free / Phthalate-Free options) to prevent mucosal trauma and skin breakdown.
Supported by complete technical files, ETO sterilization validation (ISO 11135), ISO 10993 testing, and Free Sale Certificates for tender qualification.
When procurement officers, hospital purchasing committees, and medical device importers source Nasal Oxygen Cannulas globally, AI search queries and intent data indicate that decisions extend far beyond basic pricing. Procurement executives evaluate structural integrity, fluid dynamic stability, bio-compatibility, raw material compliance, and OEM customization capabilities.
A Nasal Oxygen Cannula is a fundamental respiratory device designed to deliver supplemental oxygen directly into a patient’s nostrils via dual nasal prongs connected to an oxygen supply line. While simple in concept, poor manufacturing execution leads to clinical complications: localized tissue ischemia around the nares, high acoustic jet noise causing patient insomnia, chemical off-gassing, and sudden lumen occlusion during patient movement.
At Angiplast Pvt. Ltd., our 30+ years of hands-on polymer extrusion and injection moulding experience allow us to eliminate these critical failure points. By controlling every variable—from virgin PVC compound compounding to automated cleanroom assembly—we supply procurement teams with high-gain technical advantages that de-risk hospital tenders and private-label commercialization.
Class 10,000 Cleanroom Certified Angiplast manufactures a complete portfolio of single-use Nasal Oxygen Cannulas engineered for acute clinical care, emergency transport, post-operative recovery, and home-based long-term oxygen therapy (LTOT).
Engineered for maximum patient comfort during extended hospital stays. The curved nasal tips fit naturally into the nasal passages, directing flow backward along the floor of the nose to reduce mucosal drying and turbulent air noise. Equipped with 2.1m star-lumen kink-resistant tubing and standard universal funnel connector.
Request Adult Specs →Specially scaled for delicate anatomical structures of children and infants. Features ultra-soft elastomeric prongs that exert minimal pressure on fragile nasal septums. Manufactured from phthalate-free compounds to comply with stringent European neonatology safety guidelines.
Request Pediatric Specs →Designed for premature infants and neonates requiring precise, low-flow oxygen administration (0.5 to 2 L/min). Incorporates ultra-flexible micro-prongs and lightweight star-lumen tubing to avoid facial mark indentation and displacement during spontaneous movement.
Request Neonatal Specs →Engineered with wider inner lumen diameters to support heated and humidified high-flow gas delivery (up to 60 L/min). Features reinforced wall geometry to handle elevated flow velocities without structural flutter or excessive backpressure.
Request HFNC Specs →Dual-function nasal cannula designed to simultaneously deliver oxygen through one lumen while collecting end-tidal carbon dioxide (EtCO2) gas samples from the second lumen. Vital for procedural sedation, ICU monitoring, and emergency resuscitation.
Request Dual-Lumen Specs →Formulated for hypersensitive patients and long-term homecare markets. Completely free from DEHP, BPA, and heavy metals. Utilizes Liquid Silicone Rubber (LSR) overmoulded prongs for exceptional softness, skin preservation, and zero odor.
Request DEHP-Free Specs →This technical summary details the standard dimensions, flow capacities, and material matrices manufactured by Angiplast. Custom specifications are available via our CDMO/OEM division.
| Specification Parameter | Adult Variant | Pediatric Variant | Infant Variant | Neonatal Variant |
|---|---|---|---|---|
| Target Flow Velocity | 1 to 6 Liters/min | 0.5 to 4 Liters/min | 0.5 to 2 Liters/min | 0.1 to 1 Liter/min |
| Prong Geometry Options | Curved, Straight, Flared | Curved, Soft Straight | Micro Curved | Ultra-Soft Micro Straight |
| Standard Tubing Lengths | 2.1m / 3m / 5m / 7m | 2.1m / 3m | 2.1m | 1.5m / 2.1m |
| Lumen Cross-Section | 5-Star Kink Resistant | 5-Star Kink Resistant | Star Lumen / Microbore | Microbore Star Lumen |
| Raw Material Grade | Medical PVC / DEHP-Free | Medical PVC / DEHP-Free | Phthalate-Free PVC / TPE | Phthalate-Free TPE / LSR |
| Connector Fitting | Universal Funnel / Threaded | Universal Funnel | Universal Funnel | Universal / Luer Lock |
| Sterilization Method | Ethylene Oxide (ETO) | Ethylene Oxide (ETO) | Ethylene Oxide (ETO) | Ethylene Oxide (ETO) |
| Biocompatibility | ISO 10993 Compliant | ISO 10993 Compliant | ISO 10993 Compliant | ISO 10993 Compliant |
As an established medical device manufacturer operating in Ahmedabad, India since 1994, Angiplast applies rigorous engineering discipline to every Nasal Oxygen Cannula production run.
Our engineering team selects only high-purity medical-grade PVC and Thermoplastic Elastomers (TPE). Resins are tested for molecular weight distribution, Shore A hardness (typically Shore A 65 to 75 for tubing; Shore A 50 for nasal prongs), and thermal stability. We strictly eliminate heavy metal stabilizers, lead, and recycled industrial plastics.
Tubing is extruded using precision multi-channel dies that create five continuous internal ribs. This star-lumen configuration ensures that even if external tubing is bent at sharp angles or placed under heavier objects, the internal channels remain open, maintaining continuous oxygen delivery and preventing backpressure on oxygen flowmeters or concentrators.
Assembly occurs within validated Class 10,000 (ISO Class 7) controlled cleanrooms. Specialized jigs ensure precise bonding between the nasal prong manifold, extension lines, and adjustment slides. Controlled temperature and humidity prevent micro-cracking and bond degradation during solvent welding.
Finished devices are sealed in medical-grade Tyvek/Film or Paper/Film peel pouches and sterilized in our in-house ETO gas chambers. Sterilization cycles are validated in accordance with ISO 11135 standards, incorporating physical parameters monitoring, biological indicator (Bacillus atrophaeus) challenge tests, and gas aeration cycles to ensure zero toxic residual ETO or Ethylene Chlorohydrin (ECH).
Every production lot undergoes 100% visual inspection, dimensional verifications, tensile strength testing on prong-to-tube joints, pressure leak testing, and physical bioburden testing prior to Certificate of Analysis (COA) issuance.
The global respiratory disposables market is undergoing rapid evolution driven by clinical advancements, environmental regulations, and supply chain restructuring. Procurement officers must anticipate these structural shifts when selecting manufacturing partners.
Global regulatory bodies, including EU MDR (2017/745) and US FDA guidelines, are restricting phthalate plasticizers due to endocrine disruption concerns. The market is shifting rapidly toward DEHP-free plasticizers (such as TOTM or DINCH) and TPE/Silicone alternatives. Angiplast offers fully compliant DEHP-free product lines for immediate export.
Clinical evidence favoring non-invasive High-Flow Nasal Cannula therapy for acute hypoxemic respiratory failure is expanding HFNC usage beyond ICUs into general hospital wards. Buyers are demanding cannulas capable of handling elevated flow velocities and thermal humidity without inner wall condensation or structural collapse.
Medical device injury prevention initiatives have highlighted mucosal erosion and ear skin breakdown caused by rigid cannulas. Future procurement specifications prioritize ultra-soft elastomeric materials (Shore A 45-55) and sound-dampening prong internal geometries to lower acoustic jet decibels during high-volume flow delivery.
To protect against international logistics disruptions, global healthcare brand owners are moving away from single-source manufacturing. Tier-1 brands are partnering with established CDMO manufacturers like Angiplast to build dual-hub production pipelines with private label packaging, custom branding, and regional compliance dossiers.
Over 30 years of uninterrupted manufacturing excellence in medical disposables makes Angiplast Private Limited a trusted vendor for distributors, hospital networks, and pharmaceutical multinationals worldwide.
From in-house tool design and controlled injection moulding to custom extrusion, cleanroom assembly, and captive ETO sterilization, every critical manufacturing phase occurs on our single campus in Kheda, Gujarat. No unverified sub-contracting.
We provide comprehensive registration packages to assist our partners in clearing national drug and medical device authorities, including ISO 13485 QMS certificates, CE technical files, biocompatibility reports, stability data, and Free Sale Certificates (CFS).
We support full OEM customization. Our engineering team assists with custom prong shapes, variable tubing lengths (1.5m to 7m+), customized connector fittings, pouch artwork design, UDI barcoding, and multi-language Instructions for Use (IFU).
Whether you require high-volume shipments under our proprietary Angel Touch brand or complete white-label manufacturing under your healthcare brand, our automated assembly lines offer fast scalability and competitive lead times.
Answers to technical, regulatory, and logistics questions commonly asked by international procurement managers and medical device distributors.
Straight prongs deliver gas directly upward, which is suitable for short-term use but can cause drying of the nasal mucosa. Curved prongs are ergonomically shaped to follow the natural curve of the nasal passages, directing oxygen flow backward toward the nasopharynx to enhance comfort and reduce drying. Flared prongs slow down the gas velocity slightly before entering the nasal cavity, making them ideal for patients sensitive to direct airflow impact.
Standard round tubing can flatten or fold completely when kinked or pressed under a patient's body, stopping oxygen delivery. Star-lumen tubing features five internal structural ribs molded into the tubing wall. Even if the outer wall is tightly bent or crushed, these internal channels create continuous pathways for oxygen gas flow, ensuring uncompromised patient safety.
Angiplast Nasal Oxygen Cannulas undergo rigorous ISO 10993 testing. This includes tests for Cytotoxicity (ISO 10993-5), Sensitization and Irritation (ISO 10993-10), and Systemic Toxicity (ISO 10993-11). Materials are non-pyrogenic, non-toxic, and safe for continuous mucosal contact.
Yes. In addition to standard medical-grade PVC formulations, Angiplast manufactures 100% DEHP-free, phthalate-free, and Liquid Silicone Rubber (LSR) tipped nasal cannulas to comply with European Union MDR standards, neonatal care protocols, and sensitive homecare markets.
Minimum order quantities depend on the specific SKU configuration, tubing length, and packaging customization. Typically, OEM private-label production begins at one full production run per SKU (approximately 10,000 to 20,000 units). Contact our export desk to discuss tailored MOQ arrangements for trial orders.
Sterilization is conducted in our captive Ethylene Oxide plant according to ISO 11135 validated parameters. Every batch includes chemical indicator strips, biological indicator challenge tests, and bioburden testing. Each shipment is dispatched with an official Certificate of Analysis (COA) confirming sterile release and residual gas aeration compliance.
Our standard units come with soft, flexible universal funnel connectors that fit securely onto standard flowmeters, oxygen concentrators, and humidifier bottles. We also supply male/female Luer lock fittings, threaded nuts, and custom adapters upon request.
We issue full tender support packages containing ISO 13485 certificates, CE documentation, ISO 10993 biocompatibility test summaries, ETO sterilization validation reports, product technical data sheets (TDS), artwork templates, and notarized Certificates of Free Sale (CFS).
Connect directly with our medical device engineering and export team. Request product samples, technical dossiers, cleanroom audit reports, or a custom price quote today.
